Cult of the Lamb is very shallow and devoid of content, but the devs perfected the art of the streamerbait.

The game looks and sounds amazing, and presents the whole gameplay loop within the first hour, so if you catch a glimpse of the game on someone's stream, you will probably think "oh damn, this is really cool" and go to buy it.
If you haven't played any games in either the roguelite genre (The Binding of Isaac, Hades, Enter the Gungeon, etc) or the colony management sim genre (Dwarf Fortress, Rimworld, Oxygen not Included, etc) you might even have some fun playing it. Otherwise though you'll quickly notice there's nothing more to what you already saw on stream, and that the game doesn't live up to the level of an average game in either of those genres.

I've beaten the entirety of it in about 10 hours; the colony management is primitive and about 5-6 hours into the game my cult started playing itself with the only remaining duties being cooking and preaching, and after that I just rushed through the dungeons, of which there are only 4, all of them functionally identical. It's possible to repeat those dungeons after defeating the corresponding big boss, but outside of a tat one of the NPCs dispenses for completing the repeat dungeon for the first time, there is no point to it - they play exactly the same except you can loop 3 times through them to collect more rewards in one go (the rewards are completely meaningless by that point, because the cult will already be developed enough to maintain itself).
The combat itself is completely broken - rolling towards the enemy, striking once and rolling away by far outperforms any other tactic you can come up with, and there is pressure to avoid fooling around too much with suboptimal tactics because of the global timer which means that the cult's stats will diminish even during the dungeon time.
The enemies are copypasted from TBoI, and the bosses are just the same enemies, but bigger and with the ability to spawn smaller enemies. The only boss with the actual patterns is the final boss, and he's laughably easy, some bosses from the early floors of the aforementioned TBoI are more difficult to beat than the final boss in this game.
There are curses which act like the active items, but there's no interesting utility to them, just outputting a bit more damage.
There are tarot cards which act like the passive items, but they can be roughly divided into the two categories: minor buff to health/damage and an extremely circumstantional benefit you will never fulfill the conditions for.

I wrote a lot about the dungeon part of the game even though I think it's meant to be secondary for the colony management part.
This is because there's not much to say about the colony management part.
Followers have basic needs: hunger and hygiene, and they generate devotion. You build structures to satisfy those two needs, and structures to farm materials to build structures to satisfy those two needs. You use devotion to unlock more structures to... you get the idea. You can also preach once a day to make your followers generate cooler devotion which you use to unlock completely unsubstantial upgrades for the dungeon part. The followers level up which does pretty much nothing other than eventually allowing you to unlock perks for the cult none of which are particularly transformative.
It's all functional and completely boring, the only paradigm shift that happens in this part of the game is that eventually it loops onto itself and the cult generates enough materials which the followers use to satisfy their needs without any input on the part of the player (with the exception of cooking, and apparently the chef was on one of the promo screenshots, so I'm guessing they either removed this to put in a DLC later, it was too buggy to put in the game, or they realised that the player will literally have nothing to do at the cult anymore except preaching if the chef is present)

This shallowness, however, makes the game very approachable, and the target audience for the game, I think, is pretty clear. There is a lot of effort put into the visuals, the sound, and the Twitch integration, and seemingly a lot of money put into sponsoring the streamers to play it. The game allows you to pet a dog to tick off that meme "can you pet a dog in this game" twitter account box. The game has a fishing minigame to tick off that meme "does this game have a fishing minigame" twitter account box. When you finish the game, before the credits roll the game makes sure to plead you to recommend the game to the others.

At the end of this review I will instead recommend playing Oxygen not Included for the better colony management sim experience, and Hades for the better roguelite experience. They're just as polished as Cult of the Lamb visually and acoustically, but also are much better designed games.