I finished this game and did something I never do - immediately start a new save. As it turns out you do get a pretty different experience siding with a different faction and making some different choices!

I did like the combat, which is rare. I really liked the Spires system and the factions system. I got super into being Evil which normally I can't handle. The biggest issue I had was with bugs, which reset my favorite character back to level 1 and destroyed all his equipment. I think it's mostly linked to the Bastard's Wound DLC.
This is one of my favorites, by far.