The best roguelike ever. That's it. You can't top this game. Has enough gameplay for hundreds of hours and the expansions rise that number to the thousands. A HUGE amount of items, floors, bosses, enemies, characters, challenges, daily runs, paths, endings and even support for mods in case you didn't have enough after getting the 637 achievements (as of Repentance). I wouldn't recommend it as a starting point in the genre because it's really difficult and the amount of items gets overwhelming but at the same time it's a masterpiece that everyone should play.