DMC5 is probably the most interesting entry in the series since the first one. It really shows how how ambitious of a project it is; a new entry for the new generation that involves an insane abundance of possibilities in terms of gameplay, an insane variety of scenarios and a drastically change in style from the previous games, while still maintaining the essence of what makes DMC special, with an over exaggerated tone that does not take itself too seriously, while still being able to have serious moments here and there.
I'm not an expert on hack and slash games, but I would say that out of the three playable characters, each of them except for V (Which has a playstyle that to be honest I did not like at all) are a lot deeper than it's previous versions. Nero while having access to only one weapon and feeling like the ideal character to make new players comfortable with the game, still presents an increased amount of combos and an insane variety in it's moveset and overall it's possibilities, but who really takes the cake, however, is Dante; he can carry four weapons in both melee and ranged slots, and has also four sets of special attacks along with having two fillable meters to activate some sort of "ulti mode". Dante in this game feels like it is probably a character that you can invest thousands of hours into to master it.
Overall, DMC5 is an extremely fun time, with a very great pacing (mostly due to it abandoning the over-complicated level design of the previous games, which was one of my main complains of them) that makes you want to continue playing at all times. It has also a great style to it, with very fun and memorable cinematics.
It is definitely the DMC game that I will return to if I want to re-play one of them, but even with that, it just did not stick with me as much as DMC3 did with it's characters and story, which while this game has very memorable characters, the story line is not really great.