NOTE: This is a review of the DLC, NOT the game as a whole. I love Isaac Rebirth, see my review on it if you're curious as to why.
Afterbirth Plus is easily the worst DLC of them all. It barely adds anything at all and what's here is incredibly mediocre. Let's start with it's major additions.
The Void SUCKS. Not only is the entire floor big as all hell, it's really, REALLY easy. Imagine Basement 1, but they give you Tech X, Brimstone, and Polyphemus on the first floor, and you have The Void. You just steamroll everything in your path. Sure, you could somewhat say that about the main game, but that was much rarer to achieve. And don't even get me started on the glitchy nightmare that is Delirium. He's so glitchy and can telefrag you whenever he wants to. He's also way too damn fast. He's a fun fight, but he can be pretty annoying at times.
Greedier Mode is just harder Greed Mode. Not much else to say.
There are 2 new characters. Forgotten is fun, but Apollyon, while also fun, is way too similar to Isaac. You void bad items, just like you'd D6 bad items.
100 new items, which is fine. But there's a lot of items that are almost entirely worthless. Unique, but not good enough for another major DLC.
The 5 new challenges are AWFUL. The only one that's decent here is Pokeymans; the rest are terrible. Backasswards is just RNG, April's Fool isn't fun, Pong is pretty much just slow roll, and Ultra Hard is the worst challenge in the entire game.
Overall, AB+ just wasn't a good DLC. It's too miniscule in content, and the new stuff isn't all that great. Buy it for Repentance and nothing else.

I will almost certainly never finish binding of isaac. It's the most content-rich game probably ever made, and the commitment required to 100% (or 1000%, or platinum god, or whatever it's called at this point) the game feels absolutely impossible for me.

But it's a hell of a comfort game. doing a run and getting some mad set of items that probably don't really work together but do end up doing something weird is always entertaining to me. It doesn't really matter if I'm on a -50 win streak, because each run is unique and a laugh. Good way to kill half an hour, perfect on switch.