You slice people to instantly kill them.

Blue Moon is a song in the game and the game starts on a shot of the moon.
You also can die and also kill things with one strike, and you can wield knives.

Joker is Shiki for beta males.

You kill things.

Vampires

Gwyndolin is literally Arcueid.

Boo's Mansion/Tohno Mansion

Also Mario can die.

Consumption of hallucinogens

Protagonist has black hair and wears glasses, he also uses a knife.

Horror Vibes and Cute Girls, also death.

Kingdom Hearts is just a big moon in the sky.

Zombies

It has the moon in it.

The protagonist gets possessed by an evil entity that reincarnates.

The narrator's of both are insane

Zero is the progenitor of the Maverick Virus and gives it to Sigma who reincarnates himself while also infecting others, Zero is also a robot who wears White and Red and has Blonde Hair while X the main protagonist primarily wears Blue.

Vergil wears blue and cuts things, Dante has shoulder length hair and wears red, also the moon is on the cover.

Sonic is blue and can kill things in one hit, Knuckles is Red and from an ancient tribe. Sonic is Shiki, Knuckles is Arcueid, I am drunk.

It's a visual novel

You are a vampire

Misogyny

Moon is in the fucking title.

Pac-Man starts the game shaped like a moon, and can die, which is just like Tsukihime.

There's a DLC with Vampires, and you can recreate the cast of Tsukihime in it if you wanted to.

Originator

There's a vampire and you kill a being called Chaos

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Project Moon, Type Moon, they have Moons and are also visual novel makers.

Ken is Blonde and wears Red.

There are undead creatures.

Some levels take place at night.

My friend is extremely mixed on both of these but I'm just gonna say it's because you play a guy who cuts people and is descended from killers or some shit.

Time Vampires.

You have intercourse with women

Kohaku is like the funny devil man Hazama. Here's artwork by ILoveKohaku97 which shows her dressed as Hazama it's based.

These are both technically indie projects, the sole difference being that Yandere Simulator is irredeemably shit.

You have sexual intercourse with women

They both have music.

Both have music

DIO is a vampire who has blonde hair, and wears red, there's also night time stages.

There are night missions.

Weeb shit that defined a generation

One of the guest characters is from Melty Blood.

Japan

Both have underaged characters engaging in dangerous activity.

Moon is in the title of both

You can program Melty Blood characters into the game.

There's a lot of bad endings, also both games are visual novels.

Both have music

Sexual Content

Both games have blood in them.

Sexual Content

There's powers higher than mankind.

Also it's a visual novel.

Scary

Weird shit happens

There is a stage that starts you on the moon.